Drug interactions
Ado-trastuzumab + Fedratinib
Severity: Moderate
Ado-trastuzumab and Fedratinib: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Fedratinib is a moderate CYP3A4 inhibitor and may raise exposure to the DM1 payload of ado-trastuzumab emtansine, which is metabolized by CYP3A4.
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Other interactions of Ado-trastuzumab
Other interactions of Fedratinib
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