Drug interactions
Ado-trastuzumab emtansine + Isoniazid
Severity: Moderate
Ado-trastuzumab emtansine and Isoniazid: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Isoniazid may inhibit CYP3A4 and raise exposure to DM1, the cytotoxic payload of ado-trastuzumab emtansine.
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to see why Ado-trastuzumab emtansine and Isoniazid interact, what to do about it, and the sources.
- Mechanism of action
- Clinical management
- Evidence level
Try Pro+ free for 14 days on the web. No card needed.
Other interactions of Isoniazid
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.