Drug interactions
Afatinib + Propafenone
Severity: Moderate
Afatinib and Propafenone: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Propafenone inhibits P-glycoprotein and may increase afatinib exposure, increasing adverse effects such as diarrhea and rash.
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Other interactions of Propafenone
Other interactions of Afatinib
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