Drug interactions
Afatinib + Sunitinib
Severity: Moderate
Afatinib and Sunitinib: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Sunitinib may inhibit P-glycoprotein and BCRP, which could raise afatinib exposure and increase diarrhea, rash and other toxicities.
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Other interactions of Sunitinib
Other interactions of Afatinib
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