Drug interactions
Aficamten + Fluconazole
Severity: Major
Aficamten and Fluconazole: major interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Fluconazole can raise aficamten concentrations, increasing the negative inotropic effect and the risk of reduced ejection fraction and heart failure.
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to see why Aficamten and Fluconazole interact, what to do about it, and the sources.
- Mechanism of action
- Clinical management
- Evidence level
Free 14-day trial. No card needed.
Other interactions of Aficamten
Other interactions of Fluconazole
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
