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Drug interactions

Alogliptin-metformin + Cimetidine

Severity: Moderate

Alogliptin-metformin and Cimetidine: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Cimetidine raises metformin plasma concentrations and reduces its renal clearance, increasing the risk of metformin adverse effects including lactic acidosis, particularly in renal impairment.

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