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Drug interactions

Alprazolam + Calcium / magnesium / potassium / sodium oxybates

Severity: Contraindicated

Alprazolam and Calcium / magnesium / potassium / sodium oxybates: contraindicated interaction.

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For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Oxybates are potent CNS depressants, and adding a benzodiazepine can cause profound sedation, respiratory depression, coma or death.

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