Drug interactions
Amantadine + Difelikefalin
Severity: Moderate
Amantadine and Difelikefalin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Difelikefalin, a kappa-opioid agonist, can cause somnolence, dizziness and confusion, and amantadine may cause similar CNS effects.
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Other interactions of Amantadine
Other interactions of Difelikefalin
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