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Drug interactions

Amantadine + Metoclopramide

Severity: Major

Amantadine and Metoclopramide: major interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Metoclopramide blocks dopamine receptors, which opposes the dopaminergic effect of amantadine used for parkinsonism or drug-induced movement disorders.

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