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Drug interactions

Amiloride + Amlodipine-perindopril

Severity: Major

Amiloride and Amlodipine-perindopril: major interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Amiloride combined with an ACE inhibitor can cause significant hyperkalemia, particularly in renal impairment, diabetes or older patients.

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