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Drug interactions

Acetylsalicylic acid + Ganciclovir

Severity: Minor

Acetylsalicylic acid and Ganciclovir: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Both are eliminated partly by renal tubular secretion, so aspirin may reduce ganciclovir clearance. Higher ganciclovir exposure could worsen myelosuppression, although this is mainly a theoretical concern.

What this interaction means in plain words

Acetylsalicylic acid and Ganciclovir have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Acetylsalicylic acid belongs to Musculoskeletal; Ganciclovir belongs to Anti Virals.

Evidence level: Low

Why it happens

Competition for renal tubular organic anion secretion.

What to do

No routine adjustment is needed. Monitor blood counts and renal function as already required for ganciclovir.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Acetylsalicylic acid with Ganciclovir?

MediHelp rates the interaction as minor. Acetylsalicylic acid and Ganciclovir have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Both are eliminated partly by renal tubular secretion, so aspirin may reduce ganciclovir clearance. Higher ganciclovir exposure could worsen myelosuppression, although this is mainly a theoretical concern.

How serious is the interaction between Acetylsalicylic acid and Ganciclovir?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine adjustment is needed. Monitor blood counts and renal function as already required for ganciclovir.

What other medicines interact with Acetylsalicylic acid?

MediHelp also lists interactions of Acetylsalicylic acid with, for example, Ketorolac, Ketorolac intranasal, Abciximab. The full list is on the Acetylsalicylic acid page.

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