Drug interactions
Acetylsalicylic acid + Griseofulvin
Severity: Minor
Acetylsalicylic acid and Griseofulvin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Griseofulvin has been reported to lower salicylate concentrations, which could reduce aspirin's effect at analgesic doses. The evidence is limited and the clinical impact is uncertain.
What this interaction means in plain words
Acetylsalicylic acid and Griseofulvin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Acetylsalicylic acid belongs to Musculoskeletal; Griseofulvin belongs to Anti Fungals.
Why it happens
Possible enzyme induction or altered absorption; the mechanism is not firmly established.
What to do
Monitor therapeutic response to salicylate and increase the dose if needed. No action is required for low-dose antiplatelet use.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Acetylsalicylic acid
- Acetylsalicylic acid + Ketorolac Contraindicated
- Acetylsalicylic acid + Ketorolac intranasal Contraindicated
- Abciximab + Acetylsalicylic acid Major
- Acemetacin + Acetylsalicylic acid Major
- Acetazolamide + Acetylsalicylic acid Major
- Acetylsalicylic acid + Alteplase Major
Other interactions of Griseofulvin
Frequently asked questions
Can I take Acetylsalicylic acid with Griseofulvin?
MediHelp rates the interaction as minor. Acetylsalicylic acid and Griseofulvin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Griseofulvin has been reported to lower salicylate concentrations, which could reduce aspirin's effect at analgesic doses. The evidence is limited and the clinical impact is uncertain.
How serious is the interaction between Acetylsalicylic acid and Griseofulvin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor therapeutic response to salicylate and increase the dose if needed. No action is required for low-dose antiplatelet use.
What other medicines interact with Acetylsalicylic acid?
MediHelp also lists interactions of Acetylsalicylic acid with, for example, Ketorolac, Ketorolac intranasal, Abciximab. The full list is on the Acetylsalicylic acid page.
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