Drug interactions
Acetylsalicylic acid + Saw palmetto
Severity: Minor
Acetylsalicylic acid and Saw palmetto: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Saw palmetto has been associated with case reports of bleeding and may add to the bleeding tendency from aspirin. The evidence is limited and the effect is probably small.
What this interaction means in plain words
Acetylsalicylic acid and Saw palmetto have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Acetylsalicylic acid belongs to Musculoskeletal; Saw palmetto belongs to Gastrointestinal Tract.
Why it happens
Possible weak antiplatelet or prostaglandin synthesis inhibitory effect of saw palmetto; mechanism not established.
What to do
Ask about herbal use and monitor for bruising or bleeding. Consider stopping saw palmetto before surgery.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Acetylsalicylic acid
- Acetylsalicylic acid + Ketorolac Contraindicated
- Acetylsalicylic acid + Ketorolac intranasal Contraindicated
- Abciximab + Acetylsalicylic acid Major
- Acemetacin + Acetylsalicylic acid Major
- Acetazolamide + Acetylsalicylic acid Major
- Acetylsalicylic acid + Alteplase Major
Other interactions of Saw palmetto
- Aspirin rectal + Saw palmetto Moderate
- Dabigatran + Saw palmetto Moderate
- Desirudin + Saw palmetto Moderate
- Ketorolac + Saw palmetto Moderate
- Meclofenamate + Saw palmetto Moderate
Frequently asked questions
Can I take Acetylsalicylic acid with Saw palmetto?
MediHelp rates the interaction as minor. Acetylsalicylic acid and Saw palmetto have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Saw palmetto has been associated with case reports of bleeding and may add to the bleeding tendency from aspirin. The evidence is limited and the effect is probably small.
How serious is the interaction between Acetylsalicylic acid and Saw palmetto?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Ask about herbal use and monitor for bruising or bleeding. Consider stopping saw palmetto before surgery.
What other medicines interact with Acetylsalicylic acid?
MediHelp also lists interactions of Acetylsalicylic acid with, for example, Ketorolac, Ketorolac intranasal, Abciximab. The full list is on the Acetylsalicylic acid page.
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