Drug interactions
Acetylsalicylic acid + Telmisartan
Severity: Moderate
Acetylsalicylic acid and Telmisartan: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Aspirin at anti-inflammatory doses can reduce the blood pressure lowering effect of telmisartan and may impair renal function, particularly in elderly or volume-depleted patients. Low-dose aspirin has little effect.
What this interaction means in plain words
Acetylsalicylic acid and Telmisartan can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Acetylsalicylic acid belongs to Musculoskeletal; Telmisartan belongs to Cardiovascular.
Why it happens
Reduced vasodilatory renal prostaglandins combined with angiotensin receptor blockade can lower glomerular filtration and blunt antihypertensive action.
What to do
Monitor blood pressure, serum creatinine and potassium when high-dose aspirin is used, and ensure adequate hydration. Low-dose aspirin generally needs no change.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Acetylsalicylic acid
- Acetylsalicylic acid + Ketorolac Contraindicated
- Acetylsalicylic acid + Ketorolac intranasal Contraindicated
- Abciximab + Acetylsalicylic acid Major
- Acemetacin + Acetylsalicylic acid Major
- Acetazolamide + Acetylsalicylic acid Major
- Acetylsalicylic acid + Alteplase Major
Other interactions of Telmisartan
- Aliskiren + Telmisartan Contraindicated
- Sparsentan + Telmisartan Contraindicated
- Amifostine + Telmisartan Major
- Amiloride + Telmisartan Major
- Amlodipine-benazepril + Telmisartan Major
- Amlodipine-hydrochlorothiazide-valsartan + Telmisartan Major
Frequently asked questions
Can I take Acetylsalicylic acid with Telmisartan?
MediHelp rates the interaction as moderate. Acetylsalicylic acid and Telmisartan can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Aspirin at anti-inflammatory doses can reduce the blood pressure lowering effect of telmisartan and may impair renal function, particularly in elderly or volume-depleted patients. Low-dose aspirin has little effect.
How serious is the interaction between Acetylsalicylic acid and Telmisartan?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure, serum creatinine and potassium when high-dose aspirin is used, and ensure adequate hydration. Low-dose aspirin generally needs no change.
What other medicines interact with Acetylsalicylic acid?
MediHelp also lists interactions of Acetylsalicylic acid with, for example, Ketorolac, Ketorolac intranasal, Abciximab. The full list is on the Acetylsalicylic acid page.
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