Drug interactions
Albuterol + Indapamide
Severity: Moderate
Albuterol and Indapamide: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs lower serum potassium, and high-dose or repeated albuterol with indapamide may cause clinically significant hypokalemia. This may predispose to arrhythmias, especially in patients with cardiac disease or hypoxia.
What this interaction means in plain words
Albuterol and Indapamide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive hypokalemia from beta-2 stimulated cellular potassium uptake and diuretic-induced renal potassium loss.
What to do
Monitor serum potassium, particularly with high-dose nebulized albuterol or acute asthma and COPD exacerbations. Replace potassium as needed.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Indapamide
Frequently asked questions
Can I take Albuterol with Indapamide?
MediHelp rates the interaction as moderate. Albuterol and Indapamide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs lower serum potassium, and high-dose or repeated albuterol with indapamide may cause clinically significant hypokalemia. This may predispose to arrhythmias, especially in patients with cardiac disease or hypoxia.
How serious is the interaction between Albuterol and Indapamide?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium, particularly with high-dose nebulized albuterol or acute asthma and COPD exacerbations. Replace potassium as needed.
What other medicines interact with Indapamide?
MediHelp also lists interactions of Indapamide with, for example, Adagrasib, Amifostine, Amiodarone. The full list is on the Indapamide page.
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