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Drug interactions

Albuterol + Terbutaline

Severity: Moderate

Albuterol and Terbutaline: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Both are short-acting beta-2 agonists, so using them together duplicates therapy and increases tachycardia, tremor, hypokalemia and blood pressure effects. The risk is higher with high doses, cardiac disease or hypoxia.

What this interaction means in plain words

Albuterol and Terbutaline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Evidence level: Moderate

Why it happens

Additive beta-2 adrenergic agonism with beta-mediated intracellular potassium shift.

What to do

Avoid concurrent use of two short-acting beta-agonists and choose one agent. If both were given, monitor heart rate and serum potassium.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Albuterol with Terbutaline?

MediHelp rates the interaction as moderate. Albuterol and Terbutaline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both are short-acting beta-2 agonists, so using them together duplicates therapy and increases tachycardia, tremor, hypokalemia and blood pressure effects. The risk is higher with high doses, cardiac disease or hypoxia.

How serious is the interaction between Albuterol and Terbutaline?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent use of two short-acting beta-agonists and choose one agent. If both were given, monitor heart rate and serum potassium.

What other medicines interact with Terbutaline?

MediHelp also lists interactions of Terbutaline with, for example, Carvedilol, Droperidol, Fexinidazole. The full list is on the Terbutaline page.

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