Référentiel des médicaments
Atacicept
Atacicept is a medicine in the class miscellaneous. It is used for nephropathy.
- Classe médicamenteuse: Miscellaneous
- Indications: nephropathy
Dernière mise à jour Sources: US FDA label
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L'essentiel
- Classe médicamenteuse
- Miscellaneous
- Formes courantes
- injection
- Dosages courants
- 150 mg
- Noms commerciaux
- 1
- Pays et marchés
- 1
Indications
Mécanisme d'action
TACI-Fc fusion glycoprotein that binds BAFF (BLyS) and APRIL, reducing BAFF- and APRIL-mediated signaling and decreasing production of galactose-deficient IgA1 (Gd-IgA1), which is implicated in IgAN.
Posologie adulte habituelle (résumé de la notice)
Primary IgA nephropathy (to reduce proteinuria): 150 mg subcutaneously once weekly
Grossesse et allaitement
- Grossesse
- Unknown Human data insufficient to assess risk. Based on its mechanism it may suppress immunity in the exposed infant. No malformations in mouse or rabbit studies.
- Allaitement
- Unknown No data on milk levels or infant effects. As a large protein, infant absorption is likely low. Weigh breastfeeding benefits against the mother's need.
Effets indésirables signalés
- Infections
- Upper respiratory tract infection
- Local administration reactions
- Injection site reaction
- Injection site erythema
Contre-indications
- Serious hypersensitivity to atacicept-vymj or any excipients.
Précautions particulières
- Immunosuppression and increased risk of infections: assess for active infection before starting, monitor during treatment, and consider interruption for serious infection.
- Concomitant use with other immune-modulating drugs, including systemic corticosteroids, may increase infection risk; combined use has not been evaluated.
- May interfere with vaccine responses; complete immunizations before starting; live vaccines not recommended within 30 days before or during treatment.
Informez votre pharmacien ou votre médecin en cas de grossesse ou d'allaitement, de maladie rénale ou hépatique, d'allergies, ainsi que de tout autre médicament ou complément que vous prenez.
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Questions fréquentes
What is Atacicept used for?
Atacicept is a medicine in the class miscellaneous. It is used for Nephropathy.
What side effects have been reported with Atacicept?
Infections, Upper respiratory tract infection, Local administration reactions, Injection site reaction, Injection site erythema.
Can Atacicept be taken in pregnancy or while breastfeeding?
Pregnancy: Unknown. Human data insufficient to assess risk. Based on its mechanism it may suppress immunity in the exposed infant. No malformations in mouse or rabbit studies. Breastfeeding: Unknown. No data on milk levels or infant effects. As a large protein, infant absorption is likely low. Weigh breastfeeding benefits against the mother's need.
What does Atacicept interact with?
MediHelp does not list a checked interaction for Atacicept yet. Always tell your pharmacist about every medicine you take.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
