Référentiel des médicaments
Dexbrompheniramine
Dexbrompheniramine is a medicine in the class respiratory. It is used for allergic rhinitis.
- Classe médicamenteuse: Respiratory
- Indications: allergic rhinitis
Dernière mise à jour Sources: US FDA label
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L'essentiel
- Classe médicamenteuse
- Respiratory
- Formes courantes
- comprimé
- Dosages courants
- 2 mg
- Interactions connues
- 10 (Modérée: 9 · Mineure: 1)
- Noms commerciaux
- 1
- Pays et marchés
- 1
Indications
Mécanisme d'action
Dexbrompheniramine is the pharmacologically active dextrorotatory (S)-enantiomer of brompheniramine. It is a first-generation alkylamine (propylamine) antihistamine that competitively blocks histamine H1 receptors. This reduces histamine-mediated effects such as increased capillary permeability, vasodilation, itching, sneezing and rhinorrhoea.
Posologie adulte habituelle (résumé de la notice)
Hay fever/upper respiratory allergy symptoms (adults and children 12 years and over): 1 tablet (2 mg) orally every 4 to 6 hours; not to exceed 6 tablets in 24 hours
Grossesse et allaitement
- Grossesse
- Unknown Older antihistamine, mostly in cold and allergy combinations; limited human data with no clear link to birth defects. Loratadine or cetirizine have more pregnancy data and are preferred. Avoid combinations with decongestants in early pregnancy.
- Allaitement
- Safe LactMed: small occasional doses are not expected to harm the infant. Larger or prolonged doses may sedate the infant or reduce milk supply, especially with pseudoephedrine. A bedtime dose after the last feed limits exposure.
Effets indésirables signalés
- Drowsiness
- Excitability, especially in children
Précautions particulières
- Ask a doctor before use if you have a breathing problem such as emphysema or chronic bronchitis, glaucoma, or trouble urinating due to an enlarged prostate
- Excitability may occur, especially in children
- May cause drowsiness; use caution when driving or operating machinery
Informez votre pharmacien ou votre médecin en cas de grossesse ou d'allaitement, de maladie rénale ou hépatique, d'allergies, ainsi que de tout autre médicament ou complément que vous prenez.
Principales interactions (10)
- Amisulpride + Dexbrompheniramine Moderate
- Asenapine + Dexbrompheniramine Moderate
- Brexpiprazole + Dexbrompheniramine Moderate
- Brimonidine + Dexbrompheniramine Moderate
- Brivaracetam + Dexbrompheniramine Moderate
- Cariprazine + Dexbrompheniramine Moderate
- Dexbrompheniramine + Esketamine Moderate
- Dexbrompheniramine + Fentanyl Moderate
- Dexbrompheniramine + Levetiracetam Moderate
- Dexbrompheniramine + Lurasidone Minor
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Questions fréquentes
What is Dexbrompheniramine used for?
Dexbrompheniramine is a medicine in the class respiratory. It is used for Allergic rhinitis, Hay fever.
What side effects have been reported with Dexbrompheniramine?
Drowsiness, Excitability, especially in children.
Can Dexbrompheniramine be taken in pregnancy or while breastfeeding?
Pregnancy: Unknown. Older antihistamine, mostly in cold and allergy combinations; limited human data with no clear link to birth defects. Loratadine or cetirizine have more pregnancy data and are preferred. Avoid combinations with decongestants in early pregnancy. Breastfeeding: Safe. LactMed: small occasional doses are not expected to harm the infant. Larger or prolonged doses may sedate the infant or reduce milk supply, especially with pseudoephedrine. A bedtime dose after the last feed limits exposure.
What does Dexbrompheniramine interact with?
MediHelp lists 10 known interactions for Dexbrompheniramine. Moderate: 9 · Minor: 1. The most serious include Amisulpride, Asenapine, Brexpiprazole.
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