Référentiel des médicaments
Reboxetine
Reboxetine is a medicine in the class central nervous system. It is used for depression.
- Classe médicamenteuse: Central Nervous System
- Indications: depression
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L'essentiel
- Classe médicamenteuse
- Central Nervous System
- Formes courantes
- comprimé
- Dosages courants
- 4 mg
- Noms commerciaux
- 2
- Pays et marchés
- 2
Indications
Mécanisme d'action
Reboxetine is primarily used to treat depression but has also been found useful in the treatment of narcolepsy and panic disorders. Reboxetine is a selective inhibitor of noradrenaline reuptake. It inhibits noradrenaline reuptake in vitro to a similar extent to the tricyclic antidepressant desmethylimipramine.
Posologie adulte habituelle (résumé de la notice)
The recommended therapeutic dose is 4 mg twice a day (b.i.d.) i.e.8 mg/day administered orally, maximum daily dose should not exceed 12 mg/day.
Grossesse et allaitement
- Grossesse
- Unknown No trial data; a very limited number of exposed pregnancies showed no adverse effects. Animal studies showed no harm apart from impaired growth in rat pups. Not approved in the US. UK label: use only if benefits outweigh risks; better-studied antidepressants are preferred.
- Allaitement
- Unknown Passes into milk in low amounts; no adverse effects reported in breastfed infants (doses up to 10 mg daily). UK label: consider if benefits outweigh the risk. LactMed: use with careful infant monitoring. SSRIs such as sertraline have more data.
Effets indésirables signalés
- Dry mouth
- Insomnia
- Constipation
- Decreased appetite
- Dizziness
- Agitation
Précautions particulières
- The starting dose in patients with renal or hepatic insufficiency should be 2 mg b.i.d which can be increased based on patient tolerance.
Informez votre pharmacien ou votre médecin en cas de grossesse ou d'allaitement, de maladie rénale ou hépatique, d'allergies, ainsi que de tout autre médicament ou complément que vous prenez.
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- Dosing by age, kidney and liver function, and further dose lines
- Paediatric dosing
- Dosing in older adults
- Patient counselling points
- Food interactions
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Questions fréquentes
What is Reboxetine used for?
Reboxetine is a medicine in the class central nervous system. It is used for Depression.
What side effects have been reported with Reboxetine?
Dry mouth, Insomnia, Constipation, Decreased appetite, Dizziness, Agitation.
Can Reboxetine be taken in pregnancy or while breastfeeding?
Pregnancy: Unknown. No trial data; a very limited number of exposed pregnancies showed no adverse effects. Animal studies showed no harm apart from impaired growth in rat pups. Not approved in the US. UK label: use only if benefits outweigh risks; better-studied antidepressants are preferred. Breastfeeding: Unknown. Passes into milk in low amounts; no adverse effects reported in breastfed infants (doses up to 10 mg daily). UK label: consider if benefits outweigh the risk. LactMed: use with careful infant monitoring. SSRIs such as sertraline have more data.
What does Reboxetine interact with?
MediHelp does not list a checked interaction for Reboxetine yet. Always tell your pharmacist about every medicine you take.
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