Référentiel des médicaments
Silver sulfadiazine
Silver sulfadiazine is a medicine in the class anti bacterial. It is used for burns.
- Classe médicamenteuse: Anti Bacterial
- Indications: burns
Dernière mise à jour
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L'essentiel
- Classe médicamenteuse
- Anti Bacterial
- Formes courantes
- crème, inhalateur
- Dosages courants
- 1%, 10 g/1000 g, 10 mg/g
- Interactions connues
- 4 (Modérée: 4)
- Noms commerciaux
- 19
- Pays et marchés
- 3
Indications
Mécanisme d'action
Acts on cell membrane and cell wall
Posologie adulte habituelle (résumé de la notice)
Burn Wound Infections (2°/3°) (1% cream): Apply to thickness of 1/16 inch qDay-q12hr to burn
Grossesse et allaitement
- Grossesse
- Unsafe Burn cream: sulfadiazine and some silver are absorbed, more from large burns. No harm in rabbits. US label: contraindicated in women at or near term, as sulfonamides raise the risk of newborn kernicterus. Earlier in pregnancy use only if clearly justified.
- Allaitement
- Unknown Not known if it passes into milk; about 10% of the sulfadiazine is absorbed and sulfonamides reach milk. US label: decide whether to stop breastfeeding or the drug (kernicterus). e-lactancia: probably compatible. Avoid with a newborn, preterm, jaundiced or G6PD-deficient infant; never on the breast.
Effets indésirables signalés
- Pain
- Erythema multiforme
- Itching
- Burning
- Necrosis of the skin
Contre-indications
- Sulfa allergy
- Hypersensitivity
- Pregnant women at term or near term; premature infants, or in infants 2 months or younger
Précautions particulières
- Use caution in G6PD deficiency; hemolysis may occur
- For topical use only; avoid contact with eyes
- Although silver sulfadiazine is minimally absorbed, it reacts with body fluids to release sulfadiazine, which is absorbed and may reach substantial serum concentrations
Informez votre pharmacien ou votre médecin en cas de grossesse ou d'allaitement, de maladie rénale ou hépatique, d'allergies, ainsi que de tout autre médicament ou complément que vous prenez.
Principales interactions (4)
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- Dosing by age, kidney and liver function, and further dose lines
- Renal and hepatic dose adjustments
- Paediatric dosing
- Pharmacokinetics
- Patient counselling points
- Food interactions
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Questions fréquentes
What is Silver sulfadiazine used for?
Silver sulfadiazine is a medicine in the class anti bacterial. It is used for Burns.
What side effects have been reported with Silver sulfadiazine?
Pain, Erythema multiforme, Itching, Burning, Necrosis of the skin.
Can Silver sulfadiazine be taken in pregnancy or while breastfeeding?
Pregnancy: Unsafe. Burn cream: sulfadiazine and some silver are absorbed, more from large burns. No harm in rabbits. US label: contraindicated in women at or near term, as sulfonamides raise the risk of newborn kernicterus. Earlier in pregnancy use only if clearly justified. Breastfeeding: Unknown. Not known if it passes into milk; about 10% of the sulfadiazine is absorbed and sulfonamides reach milk. US label: decide whether to stop breastfeeding or the drug (kernicterus). e-lactancia: probably compatible. Avoid with a newborn, preterm, jaundiced or G6PD-deficient infant; never on the breast.
What does Silver sulfadiazine interact with?
MediHelp lists 4 known interactions for Silver sulfadiazine. Moderate: 4. The most serious include Allogeneic cultured keratinocytes and fibroblasts, Collagenase, Papain.
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