Référentiel des médicaments
Thiopental
Thiopental is a medicine in the class central nervous system. It is used for anesthesia.
- Classe médicamenteuse: Central Nervous System
- Indications: anesthesia
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L'essentiel
- Classe médicamenteuse
- Central Nervous System
- Formes courantes
- injection
- Dosages courants
- 1 g, 0.5 g, 500 mg
- Noms commerciaux
- 9
- Pays et marchés
- 2
Indications
Mécanisme d'action
Thiopental is a barbiturate used to induce general anesthesia, treat convulsions, and reduce intracranial pressure.
Posologie adulte habituelle (résumé de la notice)
A normal adult dose for induction of anaesthesia is 4-6 mg/kg body weight
Grossesse et allaitement
- Grossesse
- Safe FDA warns that lengthy or repeated general anaesthesia in the 3rd trimester may affect fetal brain development. UK label: can be used in pregnancy without adverse effects (long caesarean use), but only when the benefit outweighs the risk; it crosses the placenta and may depress the newborn.
- Allaitement
- Safe Very small amounts pass into milk. UK label: suspend breastfeeding for at least 12 hours or express before induction. LactMed: no waiting period is needed; breastfeed once the mother is alert. With several anaesthetics, follow the most restrictive one; watch for sleepiness.
Effets indésirables signalés
- Somnolence
- Bronchospasm
- Hypotension
- Heart arrythmia
- Myocardia depression
- Delayed wakening
Précautions particulières
- Metoclopramide and droperidol reduce the dose of thiopental sodium required to induce anaesthesia.
- Midazolam potentiates the anaesthetic effects of thiopental sodium.
- Pretreatment with probenecid has been shown to potentiate thiopental sodium anaesthesia.
Informez votre pharmacien ou votre médecin en cas de grossesse ou d'allaitement, de maladie rénale ou hépatique, d'allergies, ainsi que de tout autre médicament ou complément que vous prenez.
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- Paediatric dosing
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Questions fréquentes
What is Thiopental used for?
Thiopental is a medicine in the class central nervous system. It is used for Anesthesia.
What side effects have been reported with Thiopental?
Somnolence, Bronchospasm, Hypotension, Heart arrythmia, Myocardia depression, Delayed wakening.
Can Thiopental be taken in pregnancy or while breastfeeding?
Pregnancy: Safe. FDA warns that lengthy or repeated general anaesthesia in the 3rd trimester may affect fetal brain development. UK label: can be used in pregnancy without adverse effects (long caesarean use), but only when the benefit outweighs the risk; it crosses the placenta and may depress the newborn. Breastfeeding: Safe. Very small amounts pass into milk. UK label: suspend breastfeeding for at least 12 hours or express before induction. LactMed: no waiting period is needed; breastfeed once the mother is alert. With several anaesthetics, follow the most restrictive one; watch for sleepiness.
What does Thiopental interact with?
MediHelp does not list a checked interaction for Thiopental yet. Always tell your pharmacist about every medicine you take.
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