Interactions médicamenteuses
Atezolizumab + Cefalexin
Gravité: Mineure
Atezolizumab and Cefalexin: minor interaction.
Dernière mise à jour
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Résumé
Observational data link antibiotic exposure around the start of immune checkpoint inhibitor therapy with poorer outcomes, possibly through gut microbiome disruption. The evidence is associative and confounded by patient illness severity. The effect on any individual patient is uncertain.
Ce que signifie cette interaction, en termes simples
Atezolizumab and Cefalexin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Atezolizumab belongs to Oncology; Cefalexin belongs to Anti Bacterial.
Pourquoi elle survient
Proposed disruption of gut microbiota that may modulate antitumor immune response; not firmly established.
Conduite à tenir
Prescribe the antibiotic only when clearly indicated and keep the course short. Do not withhold needed antibiotics.
Questions à poser à votre pharmacien
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Autres interactions de Cefalexin
- Amikacin + Cefalexin Modérée
- Avelumab + Cefalexin Modérée
- Balstilimab + Cefalexin Modérée
- Bcg vaccine live + Cefalexin Modérée
- Cefalexin + Cholera vaccine Modérée
- Cefalexin + Gentamicin Modérée
Autres interactions de Atezolizumab
- Atezolizumab + Siponimod Modérée
- Atezolizumab + Piperacillin-tazobactam Mineure
Questions fréquentes
Can I take Atezolizumab with Cefalexin?
MediHelp rates the interaction as minor. Atezolizumab and Cefalexin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Observational data link antibiotic exposure around the start of immune checkpoint inhibitor therapy with poorer outcomes, possibly through gut microbiome disruption. The evidence is associative and confounded by patient illness severity. The effect on any individual patient is uncertain.
How serious is the interaction between Atezolizumab and Cefalexin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Prescribe the antibiotic only when clearly indicated and keep the course short. Do not withhold needed antibiotics.
What other medicines interact with Cefalexin?
MediHelp also lists interactions of Cefalexin with, for example, Amikacin, Avelumab, Balstilimab. The full list is on the Cefalexin page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
