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Interactions médicamenteuses

Basiliximab + Bcg vaccine live

Gravité: Contre-indiquée

Basiliximab and Bcg vaccine live: contraindicated interaction.

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Résumé

BCG is a live attenuated bacterial vaccine that can cause disseminated BCG infection in immunosuppressed patients. Basiliximab also impairs the immune response, so vaccination may not work.

Ce que signifie cette interaction, en termes simples

Basiliximab and Bcg vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Niveau de preuve: Moderate

Pourquoi elle survient

IL-2 receptor blockade suppresses T-cell activation needed to contain live attenuated mycobacteria.

Conduite à tenir

Do not give BCG to patients receiving basiliximab; use other TB prevention measures and reassess after immune recovery.

Questions à poser à votre pharmacien

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Questions fréquentes

Can I take Basiliximab with Bcg vaccine live?

MediHelp rates the interaction as contraindicated. Basiliximab and Bcg vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. BCG is a live attenuated bacterial vaccine that can cause disseminated BCG infection in immunosuppressed patients. Basiliximab also impairs the immune response, so vaccination may not work.

How serious is the interaction between Basiliximab and Bcg vaccine live?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give BCG to patients receiving basiliximab; use other TB prevention measures and reassess after immune recovery.

What other medicines interact with Basiliximab?

MediHelp also lists interactions of Basiliximab with, for example, Influenza virus vaccine quadrivalent intranasal, Measles mumps and rubella vaccine, Measles mumps and rubella vaccine live. The full list is on the Basiliximab page.

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Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.

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