Interactions médicamenteuses
Bendamustine + Dengue vaccine
Gravité: Majeure
Bendamustine and Dengue vaccine: major interaction.
Dernière mise à jour
Réservé aux professionnels de santé — à titre de référence uniquement. Cette page est un bref résumé, pas un avis médical, et ne remplace ni la notice officielle ni le jugement clinique. Vérifiez toujours avant de prescrire ou de délivrer.
Le contenu clinique de cette page n'est disponible qu'en anglais.
Résumé
Dengue vaccine is a live attenuated vaccine. In patients immunosuppressed by bendamustine, the response may be reduced and there is a risk of vaccine-related infection.
Ce que signifie cette interaction, en termes simples
Bendamustine and Dengue vaccine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Pourquoi elle survient
Cytotoxic immunosuppression and lymphodepletion impair vaccine response and permit replication of the live virus.
Conduite à tenir
Avoid live vaccine during bendamustine therapy and until immune recovery. Vaccinate before starting treatment when possible or use non-live alternatives.
Questions à poser à votre pharmacien
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Réservé aux membres Pro+
Débloquer la page complète
Créez un compte et lancez un essai Pro+ pour débloquer les conseils complets de prise en charge pour Bendamustine et Dengue vaccine, les notes complémentaires, le détail des données probantes et le vérificateur d'interactions pour une ordonnance complète.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Essayez Pro+ gratuitement pendant 14 jours sur le web. Sans carte.
Autres interactions de Bendamustine
Questions fréquentes
Can I take Bendamustine with Dengue vaccine?
MediHelp rates the interaction as major. Bendamustine and Dengue vaccine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Dengue vaccine is a live attenuated vaccine. In patients immunosuppressed by bendamustine, the response may be reduced and there is a risk of vaccine-related infection.
How serious is the interaction between Bendamustine and Dengue vaccine?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid live vaccine during bendamustine therapy and until immune recovery. Vaccinate before starting treatment when possible or use non-live alternatives.
What other medicines interact with Bendamustine?
MediHelp also lists interactions of Bendamustine with, for example, Axicabtagene ciloleucel, Brexucabtagene autoleucel, Chlorambucil. The full list is on the Bendamustine page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
