Interactions médicamenteuses
Bictegravir + Ferrous sulfate
Gravité: Modérée
Bictegravir and Ferrous sulfate: moderate interaction.
Dernière mise à jour
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Résumé
Iron binds bictegravir in the gut and can lower its absorption, risking reduced antiviral activity and resistance. The effect is largely avoided when both are taken together with food.
Ce que signifie cette interaction, en termes simples
Bictegravir and Ferrous sulfate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Pourquoi elle survient
Chelation of bictegravir by polyvalent iron cations in the gastrointestinal tract reduces absorption.
Conduite à tenir
Take bictegravir and iron together with food, or give bictegravir at least 2 hours before iron when fasting. Do not take it fasting at the same time as, or within 2 hours after, iron.
Questions à poser à votre pharmacien
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Autres interactions de Ferrous sulfate
Questions fréquentes
Can I take Bictegravir with Ferrous sulfate?
MediHelp rates the interaction as moderate. Bictegravir and Ferrous sulfate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Iron binds bictegravir in the gut and can lower its absorption, risking reduced antiviral activity and resistance. The effect is largely avoided when both are taken together with food.
How serious is the interaction between Bictegravir and Ferrous sulfate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Take bictegravir and iron together with food, or give bictegravir at least 2 hours before iron when fasting. Do not take it fasting at the same time as, or within 2 hours after, iron.
What other medicines interact with Ferrous sulfate?
MediHelp also lists interactions of Ferrous sulfate with, for example, Ciprofloxacin, Dimercaprol, Acetohydroxamic acid. The full list is on the Ferrous sulfate page.
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