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Interactions médicamenteuses

Cefalexin + Zinc

Gravité: Modérée

Cefalexin and Zinc: moderate interaction.

Dernière mise à jour

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Résumé

Oral zinc may reduce the absorption of cefalexin, with potentially lower antibiotic levels and reduced efficacy. The effect is modest and avoidable by separating the doses.

Ce que signifie cette interaction, en termes simples

Cefalexin and Zinc can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Cefalexin belongs to Anti Bacterial; Zinc belongs to Gastrointestinal Tract.

Niveau de preuve: Moderate

Pourquoi elle survient

Chelation or binding of cefalexin by zinc cations in the gastrointestinal tract, reducing absorption.

Conduite à tenir

Give oral zinc at least 3 hours after cefalexin. Monitor clinical response to the antibiotic.

Questions à poser à votre pharmacien

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Questions fréquentes

Can I take Cefalexin with Zinc?

MediHelp rates the interaction as moderate. Cefalexin and Zinc can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oral zinc may reduce the absorption of cefalexin, with potentially lower antibiotic levels and reduced efficacy. The effect is modest and avoidable by separating the doses.

How serious is the interaction between Cefalexin and Zinc?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give oral zinc at least 3 hours after cefalexin. Monitor clinical response to the antibiotic.

What other medicines interact with Cefalexin?

MediHelp also lists interactions of Cefalexin with, for example, Amikacin, Avelumab, Balstilimab. The full list is on the Cefalexin page.

Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp

Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.

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