Interactions médicamenteuses
Cefpodoxime + Cholera vaccine
Gravité: Modérée
Cefpodoxime and Cholera vaccine: moderate interaction.
Dernière mise à jour
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Résumé
The oral live attenuated cholera vaccine relies on replication of the vaccine strain in the gut. Systemic antibiotics may be active against the strain and reduce the immune response.
Ce que signifie cette interaction, en termes simples
Cefpodoxime and Cholera vaccine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Pourquoi elle survient
Antibacterial activity may inhibit replication of the live attenuated vaccine strain, lowering immunogenicity.
Conduite à tenir
Avoid giving the vaccine to patients who have taken systemic antibiotics in the previous 14 days. Delay vaccination until the antibiotic course is complete and the interval has passed.
Questions à poser à votre pharmacien
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Autres interactions de Cefpodoxime
- Aluminum hydroxide + Cefpodoxime Modérée
- Amikacin + Cefpodoxime Modérée
- Calcium carbonate + Cefpodoxime Modérée
- Calcium + Cefpodoxime Modérée
- Cefpodoxime + Cimetidine Modérée
- Cefpodoxime + Didanosine Modérée
Questions fréquentes
Can I take Cefpodoxime with Cholera vaccine?
MediHelp rates the interaction as moderate. Cefpodoxime and Cholera vaccine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. The oral live attenuated cholera vaccine relies on replication of the vaccine strain in the gut. Systemic antibiotics may be active against the strain and reduce the immune response.
How serious is the interaction between Cefpodoxime and Cholera vaccine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid giving the vaccine to patients who have taken systemic antibiotics in the previous 14 days. Delay vaccination until the antibiotic course is complete and the interval has passed.
What other medicines interact with Cefpodoxime?
MediHelp also lists interactions of Cefpodoxime with, for example, Aluminum hydroxide, Amikacin, Calcium carbonate. The full list is on the Cefpodoxime page.
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