Interactions médicamenteuses
Diclofenac + Ketorolac intranasal
Gravité: Contre-indiquée
Diclofenac and Ketorolac intranasal: contraindicated interaction.
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Résumé
Ketorolac is contraindicated with other NSAIDs because the combination increases the risk of gastrointestinal bleeding, perforation and renal impairment. Intranasal ketorolac is systemically absorbed, so the warning applies.
Ce que signifie cette interaction, en termes simples
Diclofenac and Ketorolac intranasal are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Pourquoi elle survient
Additive cyclooxygenase inhibition causing GI mucosal injury, platelet inhibition and reduced renal prostaglandins.
Conduite à tenir
Do not use together. Use one NSAID at a time and choose a non-NSAID analgesic such as paracetamol if more analgesia is needed.
Questions à poser à votre pharmacien
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Autres interactions de Diclofenac
- Diclofenac + Ketorolac Contre-indiquée
- Aceclofenac + Diclofenac Majeure
- Acemetacin + Diclofenac Majeure
- Alteplase + Diclofenac Majeure
- Amiloride + Diclofenac Majeure
- Amlodipine-hydrochlorothiazide-valsartan + Diclofenac Majeure
Questions fréquentes
Can I take Diclofenac with Ketorolac intranasal?
MediHelp rates the interaction as contraindicated. Diclofenac and Ketorolac intranasal are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Ketorolac is contraindicated with other NSAIDs because the combination increases the risk of gastrointestinal bleeding, perforation and renal impairment. Intranasal ketorolac is systemically absorbed, so the warning applies.
How serious is the interaction between Diclofenac and Ketorolac intranasal?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use together. Use one NSAID at a time and choose a non-NSAID analgesic such as paracetamol if more analgesia is needed.
What other medicines interact with Diclofenac?
MediHelp also lists interactions of Diclofenac with, for example, Ketorolac, Aceclofenac, Acemetacin. The full list is on the Diclofenac page.
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Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
