Interactions médicamenteuses
Ex vivo expanded autologous human corneal epithelial cells containing stem cells + Lidocaine
Gravité: Majeure
Ex vivo expanded autologous human corneal epithelial cells containing stem cells and Lidocaine: major interaction.
Dernière mise à jour
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Résumé
Topical lidocaine applied to the eye may be toxic to the cultured corneal epithelial cells and reduce the colony-forming capacity of the graft. This could impair engraftment and treatment success.
Ce que signifie cette interaction, en termes simples
Ex vivo expanded autologous human corneal epithelial cells containing stem cells and Lidocaine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Ex vivo expanded autologous human corneal epithelial cells containing stem cells belongs to Miscellaneous; Lidocaine belongs to Cardiovascular.
Pourquoi elle survient
Local anesthetic cytotoxicity to cultured epithelial stem cells reduces their viability.
Conduite à tenir
Avoid topical lidocaine on the graft site or cell product. Follow the product labeling for the permitted anesthetic technique around the procedure.
Questions à poser à votre pharmacien
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Autres interactions de Ex vivo expanded autologous human corneal epithelial cells containing stem cells
Autres interactions de Lidocaine
Questions fréquentes
Can I take Ex vivo expanded autologous human corneal epithelial cells containing stem cells with Lidocaine?
MediHelp rates the interaction as major. Ex vivo expanded autologous human corneal epithelial cells containing stem cells and Lidocaine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Topical lidocaine applied to the eye may be toxic to the cultured corneal epithelial cells and reduce the colony-forming capacity of the graft. This could impair engraftment and treatment success.
How serious is the interaction between Ex vivo expanded autologous human corneal epithelial cells containing stem cells and Lidocaine?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid topical lidocaine on the graft site or cell product. Follow the product labeling for the permitted anesthetic technique around the procedure.
What other medicines interact with Ex vivo expanded autologous human corneal epithelial cells containing stem cells?
MediHelp also lists interactions of Ex vivo expanded autologous human corneal epithelial cells containing stem cells with, for example, Epinephrine. The full list is on the Ex vivo expanded autologous human corneal epithelial cells containing stem cells page.
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