दवा संदर्भ
Ex vivo expanded autologous human corneal epithelial cells containing stem cells
Ex vivo expanded autologous human corneal epithelial cells containing stem cells is a medicine in the class miscellaneous.
- दवा वर्ग: Miscellaneous
अंतिम अपडेट स्रोत: EMA SmPC
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
मुख्य तथ्य
- दवा वर्ग
- Miscellaneous
- ATC कोड
- S01XA19
- ज्ञात अंतःक्रियाएँ
- 2 (गंभीर: 2)
- ब्रांड नाम
- 1
- देश और बाज़ार
- 1
यह कैसे काम करती है
Replaces corneal epithelium and lost limbal stem cells in patients whose limbus has been destroyed by ocular burns. The administered stem cells multiply, differentiate and migrate to regenerate corneal epithelium and maintain a stem cell reservoir.
वयस्कों की सामान्य खुराक (लेबल सारांश)
Moderate to severe limbal stem cell deficiency due to ocular burns: 79,000 - 316,000 cells/ cm², corresponding to 1 cm² of product/cm² of defect, by implantation, single treatment; may be repeated if the treating physician considers it indicated
गर्भावस्था और स्तनपान
- गर्भावस्था
- Unknown Corneal implant of the patient's own stem cells (Holoclar), applied to one eye. No data in pregnancy and no animal studies; little or no systemic exposure is expected. EU label: as a precaution, avoid implantation during pregnancy.
- स्तनपान
- Unknown No data. Little or no exposure of the infant is expected from an eye implant. EU label: not recommended to implant while breastfeeding, as a precaution; the eye medicines given after surgery should also be checked.
रिपोर्ट किए गए दुष्प्रभाव
- Eye pain
- Corneal epithelium defect
- Conjunctival haemorrhage
- Glaucoma / increased intraocular pressure
- Corneal perforation
- Ulcerative keratitis
प्रतिसंकेत
- Hypersensitivity to any of the excipients or to bovine serum and murine 3T3-J2 cells
किन्हें सावधानी रखनी चाहिए
- For autologous use only; must never be given to other patients or if labels and lot number do not match the patient's identity
- Risk of transmission of infectious agents; monitor patients for signs and symptoms of infection after treatment
- Contains lethally-irradiated murine 3T3 fibroblast cells and may contain traces of foetal bovine serum; do not treat patients with known hypersensitivity to mice or foetal bovine serum
गर्भावस्था या स्तनपान, किडनी या लिवर के रोग, एलर्जी और आप जो भी अन्य दवा या सप्लीमेंट लेते हैं, उसके बारे में अपने फार्मासिस्ट या डॉक्टर को बताएँ।
मुख्य इंटरैक्शन (2)
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Ex vivo expanded autologous human corneal epithelial cells containing stem cells का पूरा मोनोग्राफ खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें: खुराक, गर्भावस्था और स्तनपान, दुष्प्रभाव, चेतावनियाँ और सभी इंटरैक्शन।
- Dosing by age, kidney and liver function, and further dose lines
- Dosing in older adults
- How to give it
- Pharmacokinetics
- Patient counselling points
वेब पर Pro+ को 7 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
अक्सर पूछे जाने वाले प्रश्न
What is Ex vivo expanded autologous human corneal epithelial cells containing stem cells used for?
Ex vivo expanded autologous human corneal epithelial cells containing stem cells is a medicine in the class miscellaneous.
What side effects have been reported with Ex vivo expanded autologous human corneal epithelial cells containing stem cells?
Eye pain, Corneal epithelium defect, Conjunctival haemorrhage, Glaucoma / increased intraocular pressure, Corneal perforation, Ulcerative keratitis.
Can Ex vivo expanded autologous human corneal epithelial cells containing stem cells be taken in pregnancy or while breastfeeding?
Pregnancy: Unknown. Corneal implant of the patient's own stem cells (Holoclar), applied to one eye. No data in pregnancy and no animal studies; little or no systemic exposure is expected. EU label: as a precaution, avoid implantation during pregnancy. Breastfeeding: Unknown. No data. Little or no exposure of the infant is expected from an eye implant. EU label: not recommended to implant while breastfeeding, as a precaution; the eye medicines given after surgery should also be checked.
What does Ex vivo expanded autologous human corneal epithelial cells containing stem cells interact with?
MediHelp lists 2 known interactions for Ex vivo expanded autologous human corneal epithelial cells containing stem cells. Major: 2. The most serious include Epinephrine, Lidocaine.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
