दवाओं की अंतःक्रिया
Adenovirus types 4 and 7 live + Irinotecan
गंभीरता: गंभीर
Adenovirus types 4 and 7 live and Irinotecan: major interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Irinotecan is myelosuppressive and immunosuppressive, so a live oral adenovirus vaccine may replicate excessively or fail to provoke adequate immunity. This raises the risk of vaccine-related infection and reduced protection.
इस इंटरैक्शन का सरल भाषा में अर्थ
Adenovirus types 4 and 7 live and Irinotecan can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
ऐसा क्यों होता है
Cytotoxic immunosuppression impairs the immune response to live attenuated virus, allowing uncontrolled replication and reducing vaccine efficacy.
क्या करें
Avoid live vaccines during irinotecan therapy and for at least 3 months after stopping, unless the immune status is confirmed to have recovered. Give vaccines before starting chemotherapy where possible.
फार्मासिस्ट से क्या पूछें
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Adenovirus types 4 and 7 live और Irinotecan की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Irinotecan के अन्य इंटरैक्शन
- Clozapine + Irinotecan निषिद्ध
- Irinotecan + Sacituzumab govitecan निषिद्ध
- Apalutamide + Irinotecan गंभीर
- Atazanavir + Irinotecan गंभीर
- Carbamazepine + Irinotecan गंभीर
- Clarithromycin + Irinotecan गंभीर
अक्सर पूछे जाने वाले प्रश्न
Can I take Adenovirus types 4 and 7 live with Irinotecan?
MediHelp rates the interaction as major. Adenovirus types 4 and 7 live and Irinotecan can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Irinotecan is myelosuppressive and immunosuppressive, so a live oral adenovirus vaccine may replicate excessively or fail to provoke adequate immunity. This raises the risk of vaccine-related infection and reduced protection.
How serious is the interaction between Adenovirus types 4 and 7 live and Irinotecan?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid live vaccines during irinotecan therapy and for at least 3 months after stopping, unless the immune status is confirmed to have recovered. Give vaccines before starting chemotherapy where possible.
What other medicines interact with Irinotecan?
MediHelp also lists interactions of Irinotecan with, for example, Clozapine, Sacituzumab govitecan, Apalutamide. The full list is on the Irinotecan page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
