दवाओं की अंतःक्रिया
Alogliptin-metformin + Entecavir
गंभीरता: मध्यम
Alogliptin-metformin and Entecavir: moderate interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Entecavir, a nucleoside analogue, has been associated with lactic acidosis and severe hepatomegaly with steatosis. Metformin carries its own risk of lactic acidosis, so using both may add to that risk, particularly in patients with renal or hepatic impairment.
इस इंटरैक्शन का सरल भाषा में अर्थ
Alogliptin-metformin and Entecavir can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Alogliptin-metformin belongs to Endocrine; Entecavir belongs to Anti Virals.
ऐसा क्यों होता है
Additive risk of lactic acidosis through mitochondrial toxicity (entecavir) and impaired lactate clearance (metformin); no direct pharmacokinetic interaction is established.
क्या करें
Monitor renal and hepatic function periodically and educate the patient to report nausea, abdominal pain, malaise or rapid breathing. Check lactate and stop metformin if lactic acidosis is suspected.
फार्मासिस्ट से क्या पूछें
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Alogliptin-metformin और Entecavir की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 7 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Alogliptin-metformin के अन्य इंटरैक्शन
Entecavir के अन्य इंटरैक्शन
अक्सर पूछे जाने वाले प्रश्न
Can I take Alogliptin-metformin with Entecavir?
MediHelp rates the interaction as moderate. Alogliptin-metformin and Entecavir can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Entecavir, a nucleoside analogue, has been associated with lactic acidosis and severe hepatomegaly with steatosis. Metformin carries its own risk of lactic acidosis, so using both may add to that risk, particularly in patients with renal or hepatic impairment.
How serious is the interaction between Alogliptin-metformin and Entecavir?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor renal and hepatic function periodically and educate the patient to report nausea, abdominal pain, malaise or rapid breathing. Check lactate and stop metformin if lactic acidosis is suspected.
What other medicines interact with Alogliptin-metformin?
MediHelp also lists interactions of Alogliptin-metformin with, for example, Clozapine, Contrast media, Diatrizoate. The full list is on the Alogliptin-metformin page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
