दवाओं की अंतःक्रिया
Alogliptin-metformin + Niacin
गंभीरता: मध्यम
Alogliptin-metformin and Niacin: moderate interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Niacin at lipid-lowering doses can worsen insulin resistance and raise blood glucose. This may reduce control in patients with diabetes taking metformin.
इस इंटरैक्शन का सरल भाषा में अर्थ
Alogliptin-metformin and Niacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Alogliptin-metformin belongs to Endocrine; Niacin belongs to Cardiovascular.
ऐसा क्यों होता है
Niacin induces insulin resistance and increases hepatic glucose output, opposing antidiabetic therapy.
क्या करें
Monitor glucose and HbA1c after starting or increasing niacin and adjust antidiabetic therapy as needed. Consider an alternative lipid-lowering agent if control worsens significantly.
फार्मासिस्ट से क्या पूछें
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Alogliptin-metformin और Niacin की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Alogliptin-metformin के अन्य इंटरैक्शन
Niacin के अन्य इंटरैक्शन
अक्सर पूछे जाने वाले प्रश्न
Can I take Alogliptin-metformin with Niacin?
MediHelp rates the interaction as moderate. Alogliptin-metformin and Niacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Niacin at lipid-lowering doses can worsen insulin resistance and raise blood glucose. This may reduce control in patients with diabetes taking metformin.
How serious is the interaction between Alogliptin-metformin and Niacin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor glucose and HbA1c after starting or increasing niacin and adjust antidiabetic therapy as needed. Consider an alternative lipid-lowering agent if control worsens significantly.
What other medicines interact with Alogliptin-metformin?
MediHelp also lists interactions of Alogliptin-metformin with, for example, Clozapine, Contrast media, Diatrizoate. The full list is on the Alogliptin-metformin page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।