दवाओं की अंतःक्रिया
Alogliptin-pioglitazone + Cannabidiol
गंभीरता: मध्यम
Alogliptin-pioglitazone and Cannabidiol: moderate interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Cannabidiol may inhibit CYP2C8, the main enzyme clearing pioglitazone, and could raise pioglitazone levels. This may increase the risk of fluid retention, edema, weight gain and hypoglycemia.
इस इंटरैक्शन का सरल भाषा में अर्थ
Alogliptin-pioglitazone and Cannabidiol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Alogliptin-pioglitazone belongs to Endocrine; Cannabidiol belongs to Central Nervous System.
ऐसा क्यों होता है
Inhibition of CYP2C8-mediated pioglitazone metabolism.
क्या करें
Monitor for edema, weight gain and glycemic changes when cannabidiol is started, and reduce the pioglitazone dose if adverse effects appear.
फार्मासिस्ट से क्या पूछें
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Alogliptin-pioglitazone और Cannabidiol की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Alogliptin-pioglitazone के अन्य इंटरैक्शन
Cannabidiol के अन्य इंटरैक्शन
अक्सर पूछे जाने वाले प्रश्न
Can I take Alogliptin-pioglitazone with Cannabidiol?
MediHelp rates the interaction as moderate. Alogliptin-pioglitazone and Cannabidiol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Cannabidiol may inhibit CYP2C8, the main enzyme clearing pioglitazone, and could raise pioglitazone levels. This may increase the risk of fluid retention, edema, weight gain and hypoglycemia.
How serious is the interaction between Alogliptin-pioglitazone and Cannabidiol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for edema, weight gain and glycemic changes when cannabidiol is started, and reduce the pioglitazone dose if adverse effects appear.
What other medicines interact with Alogliptin-pioglitazone?
MediHelp also lists interactions of Alogliptin-pioglitazone with, for example, Gemfibrozil, Insulin aspart, Insulin degludec. The full list is on the Alogliptin-pioglitazone page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।