दवाओं की अंतःक्रिया
Alogliptin-pioglitazone + Daprodustat
गंभीरता: मध्यम
Alogliptin-pioglitazone and Daprodustat: moderate interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Pioglitazone is a weak CYP2C8 inhibitor, whereas daprodustat is a CYP2C8 substrate whose exposure rises with strong inhibitors such as gemfibrozil. A modest increase in daprodustat levels is possible, which could increase hemoglobin and thrombotic risk.
इस इंटरैक्शन का सरल भाषा में अर्थ
Alogliptin-pioglitazone and Daprodustat can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Alogliptin-pioglitazone belongs to Endocrine; Daprodustat belongs to Endocrine.
ऐसा क्यों होता है
Inhibition of CYP2C8-mediated daprodustat metabolism.
क्या करें
Monitor hemoglobin and adjust the daprodustat dose accordingly when pioglitazone is started or stopped.
फार्मासिस्ट से क्या पूछें
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Alogliptin-pioglitazone और Daprodustat की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Alogliptin-pioglitazone के अन्य इंटरैक्शन
Daprodustat के अन्य इंटरैक्शन
अक्सर पूछे जाने वाले प्रश्न
Can I take Alogliptin-pioglitazone with Daprodustat?
MediHelp rates the interaction as moderate. Alogliptin-pioglitazone and Daprodustat can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Pioglitazone is a weak CYP2C8 inhibitor, whereas daprodustat is a CYP2C8 substrate whose exposure rises with strong inhibitors such as gemfibrozil. A modest increase in daprodustat levels is possible, which could increase hemoglobin and thrombotic risk.
How serious is the interaction between Alogliptin-pioglitazone and Daprodustat?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor hemoglobin and adjust the daprodustat dose accordingly when pioglitazone is started or stopped.
What other medicines interact with Alogliptin-pioglitazone?
MediHelp also lists interactions of Alogliptin-pioglitazone with, for example, Gemfibrozil, Insulin aspart, Insulin degludec. The full list is on the Alogliptin-pioglitazone page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
