दवाओं की अंतःक्रिया
Alteplase + Tranexamic acid
गंभीरता: गंभीर
Alteplase and Tranexamic acid: major interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Tranexamic acid blocks fibrinolysis and therefore directly opposes the clot-dissolving action of alteplase. This can reduce thrombolytic efficacy, and it is also relevant that tranexamic acid is used to reverse thrombolytic-related bleeding.
इस इंटरैक्शन का सरल भाषा में अर्थ
Alteplase and Tranexamic acid can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Alteplase belongs to Cardiovascular; Tranexamic acid belongs to Cardiovascular.
ऐसा क्यों होता है
Pharmacodynamic antagonism: tranexamic acid blocks lysine binding sites on plasminogen, preventing plasmin formation and fibrin degradation.
क्या करें
Avoid concurrent use when thrombolysis is intended. Use tranexamic acid only deliberately to treat life-threatening alteplase-related bleeding.
फार्मासिस्ट से क्या पूछें
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Alteplase और Tranexamic acid की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Alteplase के अन्य इंटरैक्शन
- Alteplase + Defibrotide निषिद्ध
- Alteplase + Reteplase निषिद्ध
- Alteplase + Tenecteplase निषिद्ध
- Acetylsalicylic acid + Alteplase गंभीर
- Alteplase + Apixaban गंभीर
- Alteplase + Argatroban गंभीर
Tranexamic acid के अन्य इंटरैक्शन
- Dienogest / estradiol valerate + Tranexamic acid निषिद्ध
- Ethinyl estradiol-drospirenone + Tranexamic acid निषिद्ध
- Ethinyl estradiol-levonorgestrel + Tranexamic acid निषिद्ध
- Ethinyl estradiol-norgestimate + Tranexamic acid निषिद्ध
- Ethinylestradiol + Tranexamic acid निषिद्ध
- Mestranol + Tranexamic acid निषिद्ध
अक्सर पूछे जाने वाले प्रश्न
Can I take Alteplase with Tranexamic acid?
MediHelp rates the interaction as major. Alteplase and Tranexamic acid can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Tranexamic acid blocks fibrinolysis and therefore directly opposes the clot-dissolving action of alteplase. This can reduce thrombolytic efficacy, and it is also relevant that tranexamic acid is used to reverse thrombolytic-related bleeding.
How serious is the interaction between Alteplase and Tranexamic acid?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent use when thrombolysis is intended. Use tranexamic acid only deliberately to treat life-threatening alteplase-related bleeding.
What other medicines interact with Alteplase?
MediHelp also lists interactions of Alteplase with, for example, Defibrotide, Reteplase, Tenecteplase. The full list is on the Alteplase page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
