दवाओं की अंतःक्रिया
Amifostine + Losartan
गंभीरता: गंभीर
Amifostine and Losartan: major interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Amifostine commonly causes hypotension, and antihypertensives such as losartan can worsen the fall in blood pressure. At chemotherapeutic doses of amifostine, severe hypotension is a concern.
इस इंटरैक्शन का सरल भाषा में अर्थ
Amifostine and Losartan can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Amifostine belongs to Miscellaneous; Losartan belongs to Cardiovascular.
ऐसा क्यों होता है
Additive pharmacodynamic hypotensive effects of the two drugs.
क्या करें
For chemotherapeutic amifostine doses, withhold losartan for 24 hours beforehand; if it cannot be withheld, do not give amifostine. At lower radioprotective doses, monitor blood pressure closely and ensure hydration.
फार्मासिस्ट से क्या पूछें
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Amifostine और Losartan की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 7 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Losartan के अन्य इंटरैक्शन
Amifostine के अन्य इंटरैक्शन
अक्सर पूछे जाने वाले प्रश्न
Can I take Amifostine with Losartan?
MediHelp rates the interaction as major. Amifostine and Losartan can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Amifostine commonly causes hypotension, and antihypertensives such as losartan can worsen the fall in blood pressure. At chemotherapeutic doses of amifostine, severe hypotension is a concern.
How serious is the interaction between Amifostine and Losartan?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: For chemotherapeutic amifostine doses, withhold losartan for 24 hours beforehand; if it cannot be withheld, do not give amifostine. At lower radioprotective doses, monitor blood pressure closely and ensure hydration.
What other medicines interact with Losartan?
MediHelp also lists interactions of Losartan with, for example, Aliskiren, Sparsentan, Amiloride. The full list is on the Losartan page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
