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दवाओं की अंतःक्रिया

Amiodarone + Vandetanib

गंभीरता: निषिद्ध

Amiodarone and Vandetanib: contraindicated interaction.

अंतिम अपडेट

केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।

इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।

सारांश

Vandetanib markedly prolongs the QT interval and its labeling advises avoiding other QT-prolonging drugs. With amiodarone, whose half-life is very long, the risk of torsades de pointes and sudden death is significantly increased.

इस इंटरैक्शन का सरल भाषा में अर्थ

Amiodarone and Vandetanib are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Amiodarone belongs to Cardiovascular; Vandetanib belongs to Oncology.

साक्ष्य स्तर: High

ऐसा क्यों होता है

Additive QT prolongation through repolarizing potassium channel blockade.

क्या करें

Avoid the combination and choose an alternative therapy. Do not start vandetanib while amiodarone is still present in the body unless benefits clearly outweigh risks, with close ECG and electrolyte monitoring.

फार्मासिस्ट से क्या पूछें

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Pro+ सदस्यों के लिए

पूरा पेज खोलें

Amiodarone और Vandetanib की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।

अक्सर पूछे जाने वाले प्रश्न

Can I take Amiodarone with Vandetanib?

MediHelp rates the interaction as contraindicated. Amiodarone and Vandetanib are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Vandetanib markedly prolongs the QT interval and its labeling advises avoiding other QT-prolonging drugs. With amiodarone, whose half-life is very long, the risk of torsades de pointes and sudden death is significantly increased.

How serious is the interaction between Amiodarone and Vandetanib?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination and choose an alternative therapy. Do not start vandetanib while amiodarone is still present in the body unless benefits clearly outweigh risks, with close ECG and electrolyte monitoring.

What other medicines interact with Amiodarone?

MediHelp also lists interactions of Amiodarone with, for example, Amisulpride, Arsenic trioxide, Dofetilide. The full list is on the Amiodarone page.

MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर

MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।

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