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Amitriptyline + Umeclidinium-vilanterol

गंभीरता: गंभीर

Amitriptyline and Umeclidinium-vilanterol: major interaction.

अंतिम अपडेट स्रोत: US FDA label

केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।

इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।

सारांश

Amitriptyline can potentiate the cardiovascular effects of vilanterol and prolongs the QT interval. It also has anticholinergic effects that add to those of umeclidinium, such as dry mouth, urinary retention and tachycardia.

इस इंटरैक्शन का सरल भाषा में अर्थ

Amitriptyline and Umeclidinium-vilanterol can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.

Amitriptyline belongs to Central Nervous System; Umeclidinium-vilanterol belongs to Respiratory.

साक्ष्य स्तर: Moderate

ऐसा क्यों होता है

Additive adrenergic stimulation, QT prolongation and anticholinergic effects.

क्या करें

Use only with monitoring of ECG, heart rate and blood pressure, and watch for anticholinergic effects. Consider a non-tricyclic antidepressant when feasible.

फार्मासिस्ट से क्या पूछें

  • Does the benefit of taking both outweigh the risk in my case?
  • Do I need any blood test, ECG or other check while on both?
  • What early warning signs should I watch for, and what should I do if they appear?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Pro+ सदस्यों के लिए

पूरा पेज खोलें

Amitriptyline और Umeclidinium-vilanterol की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

वेब पर Pro+ को 7 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।

संदर्भ

अक्सर पूछे जाने वाले प्रश्न

Can I take Amitriptyline with Umeclidinium-vilanterol?

MediHelp rates the interaction as major. Amitriptyline and Umeclidinium-vilanterol can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Amitriptyline can potentiate the cardiovascular effects of vilanterol and prolongs the QT interval. It also has anticholinergic effects that add to those of umeclidinium, such as dry mouth, urinary retention and tachycardia.

How serious is the interaction between Amitriptyline and Umeclidinium-vilanterol?

MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use only with monitoring of ECG, heart rate and blood pressure, and watch for anticholinergic effects. Consider a non-tricyclic antidepressant when feasible.

What other medicines interact with Umeclidinium-vilanterol?

MediHelp also lists interactions of Umeclidinium-vilanterol with, for example, Aclidinium, Amiodarone, Amoxapine. The full list is on the Umeclidinium-vilanterol page.

MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर

MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।

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