दवाओं की अंतःक्रिया
Amlodipine-olmesartan-hydrochlorothiazide + Etodolac
गंभीरता: गंभीर
Amlodipine-olmesartan-hydrochlorothiazide and Etodolac: major interaction.
अंतिम अपडेट स्रोत: US FDA label
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
NSAIDs such as etodolac can reduce the antihypertensive effect of olmesartan and hydrochlorothiazide. In combination with an ARB and a diuretic they increase the risk of acute kidney injury and hyperkalemia, especially in older or volume-depleted patients.
इस इंटरैक्शन का सरल भाषा में अर्थ
Amlodipine-olmesartan-hydrochlorothiazide and Etodolac can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Amlodipine-olmesartan-hydrochlorothiazide belongs to Cardiovascular; Etodolac belongs to Musculoskeletal.
ऐसा क्यों होता है
NSAID inhibition of renal prostaglandin synthesis reduces renal perfusion and sodium excretion, antagonizing antihypertensive effects and impairing renal function.
क्या करें
Avoid regular use where possible and prefer paracetamol. If an NSAID is required, use the lowest dose for the shortest time and monitor blood pressure, creatinine and potassium.
फार्मासिस्ट से क्या पूछें
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Amlodipine-olmesartan-hydrochlorothiazide और Etodolac की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 7 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
संदर्भ
Amlodipine-olmesartan-hydrochlorothiazide के अन्य इंटरैक्शन
- Aliskiren + Amlodipine-olmesartan-hydrochlorothiazide निषिद्ध
- Amlodipine-olmesartan-hydrochlorothiazide + Dofetilide निषिद्ध
- Amlodipine-olmesartan-hydrochlorothiazide + Sparsentan निषिद्ध
- Acemetacin + Amlodipine-olmesartan-hydrochlorothiazide गंभीर
- Aldesleukin + Amlodipine-olmesartan-hydrochlorothiazide गंभीर
- Amifostine + Amlodipine-olmesartan-hydrochlorothiazide गंभीर
Etodolac के अन्य इंटरैक्शन
- Etodolac + Ketorolac निषिद्ध
- Etodolac + Ketorolac intranasal निषिद्ध
- Aceclofenac + Etodolac गंभीर
- Acemetacin + Etodolac गंभीर
- Acetylsalicylic acid + Etodolac गंभीर
- Alteplase + Etodolac गंभीर
अक्सर पूछे जाने वाले प्रश्न
Can I take Amlodipine-olmesartan-hydrochlorothiazide with Etodolac?
MediHelp rates the interaction as major. Amlodipine-olmesartan-hydrochlorothiazide and Etodolac can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. NSAIDs such as etodolac can reduce the antihypertensive effect of olmesartan and hydrochlorothiazide. In combination with an ARB and a diuretic they increase the risk of acute kidney injury and hyperkalemia, especially in older or volume-depleted patients.
How serious is the interaction between Amlodipine-olmesartan-hydrochlorothiazide and Etodolac?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid regular use where possible and prefer paracetamol. If an NSAID is required, use the lowest dose for the shortest time and monitor blood pressure, creatinine and potassium.
What other medicines interact with Amlodipine-olmesartan-hydrochlorothiazide?
MediHelp also lists interactions of Amlodipine-olmesartan-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Amlodipine-olmesartan-hydrochlorothiazide page.
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MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
