दवाओं की अंतःक्रिया
Amobarbital + Tinidazole
गंभीरता: मध्यम
Amobarbital and Tinidazole: moderate interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Barbiturates induce CYP3A4 and other hepatic enzymes, which can speed tinidazole clearance and lower its concentrations. This may reduce efficacy in infections such as giardiasis or anaerobic infections, although the clinical impact has not been well quantified.
इस इंटरैक्शन का सरल भाषा में अर्थ
Amobarbital and Tinidazole can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amobarbital belongs to Central Nervous System; Tinidazole belongs to Anti Parasitic.
ऐसा क्यों होता है
Amobarbital induces hepatic CYP enzymes including CYP3A4, increasing tinidazole metabolism.
क्या करें
Monitor for clinical response to tinidazole and consider a longer course or an alternative agent if treatment fails. Be aware that the induction effect persists for some time after the barbiturate is stopped.
फार्मासिस्ट से क्या पूछें
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Amobarbital और Tinidazole की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Tinidazole के अन्य इंटरैक्शन
- Disulfiram + Tinidazole निषिद्ध
- Ethanol + Tinidazole गंभीर
- Fexinidazole + Tinidazole गंभीर
- Lopinavir + Tinidazole गंभीर
- Nilotinib + Tinidazole गंभीर
- Ritonavir + Tinidazole गंभीर
Amobarbital के अन्य इंटरैक्शन
अक्सर पूछे जाने वाले प्रश्न
Can I take Amobarbital with Tinidazole?
MediHelp rates the interaction as moderate. Amobarbital and Tinidazole can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Barbiturates induce CYP3A4 and other hepatic enzymes, which can speed tinidazole clearance and lower its concentrations. This may reduce efficacy in infections such as giardiasis or anaerobic infections, although the clinical impact has not been well quantified.
How serious is the interaction between Amobarbital and Tinidazole?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for clinical response to tinidazole and consider a longer course or an alternative agent if treatment fails. Be aware that the induction effect persists for some time after the barbiturate is stopped.
What other medicines interact with Tinidazole?
MediHelp also lists interactions of Tinidazole with, for example, Disulfiram, Ethanol, Fexinidazole. The full list is on the Tinidazole page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
