दवाओं की अंतःक्रिया
Amoxapine + Procarbazine
गंभीरता: निषिद्ध
Amoxapine and Procarbazine: contraindicated interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Procarbazine has monoamine oxidase inhibitor activity, and amoxapine is a tricyclic antidepressant that inhibits noradrenaline and serotonin reuptake. Together they can cause serotonin syndrome or hypertensive reactions, with agitation, hyperthermia, autonomic instability and seizures.
इस इंटरैक्शन का सरल भाषा में अर्थ
Amoxapine and Procarbazine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
ऐसा क्यों होता है
MAO inhibition combined with reuptake inhibition raises synaptic monoamine concentrations, with additive serotonergic and adrenergic effects.
क्या करें
Avoid the combination. Leave a washout period of at least 14 days after stopping procarbazine before starting amoxapine, and the reverse as well.
फार्मासिस्ट से क्या पूछें
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Amoxapine और Procarbazine की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Procarbazine के अन्य इंटरैक्शन
- Adenovirus types 4 and 7 live + Procarbazine निषिद्ध
- Amitriptyline + Procarbazine निषिद्ध
- Atomoxetine + Procarbazine निषिद्ध
- Bcg vaccine live + Procarbazine निषिद्ध
- Brimonidine + Procarbazine निषिद्ध
- Buspirone + Procarbazine निषिद्ध
अक्सर पूछे जाने वाले प्रश्न
Can I take Amoxapine with Procarbazine?
MediHelp rates the interaction as contraindicated. Amoxapine and Procarbazine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Procarbazine has monoamine oxidase inhibitor activity, and amoxapine is a tricyclic antidepressant that inhibits noradrenaline and serotonin reuptake. Together they can cause serotonin syndrome or hypertensive reactions, with agitation, hyperthermia, autonomic instability and seizures.
How serious is the interaction between Amoxapine and Procarbazine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination. Leave a washout period of at least 14 days after stopping procarbazine before starting amoxapine, and the reverse as well.
What other medicines interact with Procarbazine?
MediHelp also lists interactions of Procarbazine with, for example, Adenovirus types 4 and 7 live, Amitriptyline, Atomoxetine. The full list is on the Procarbazine page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
