दवाओं की अंतःक्रिया
Anagrelide + Ivosidenib
गंभीरता: गंभीर
Anagrelide and Ivosidenib: major interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Ivosidenib is associated with QT prolongation, and anagrelide has a similar effect, so the combination may increase the risk of torsades de pointes. The legacy description of a QT decrease is not consistent with the known effects of either drug.
इस इंटरैक्शन का सरल भाषा में अर्थ
Anagrelide and Ivosidenib can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Anagrelide belongs to Cardiovascular; Ivosidenib belongs to Oncology.
ऐसा क्यों होता है
Additive pharmacodynamic QT prolongation; ivosidenib is also a CYP3A4 inducer, which may lower anagrelide exposure.
क्या करें
Avoid the combination if possible. If used together, monitor ECG and electrolytes regularly and reduce or stop therapy if QTc becomes markedly prolonged.
फार्मासिस्ट से क्या पूछें
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Anagrelide और Ivosidenib की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Anagrelide के अन्य इंटरैक्शन
- Anagrelide + Panobinostat निषिद्ध
- Anagrelide + Pimozide निषिद्ध
- Anagrelide + Thioridazine निषिद्ध
- Anagrelide + Vandetanib निषिद्ध
- Abrocitinib + Anagrelide गंभीर
- Alfuzosin + Anagrelide गंभीर
Ivosidenib के अन्य इंटरैक्शन
- Alfuzosin + Ivosidenib गंभीर
- Amiodarone + Ivosidenib गंभीर
- Amisulpride + Ivosidenib गंभीर
- Amitriptyline + Ivosidenib गंभीर
- Amobarbital + Ivosidenib गंभीर
- Apalutamide + Ivosidenib गंभीर
अक्सर पूछे जाने वाले प्रश्न
Can I take Anagrelide with Ivosidenib?
MediHelp rates the interaction as major. Anagrelide and Ivosidenib can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Ivosidenib is associated with QT prolongation, and anagrelide has a similar effect, so the combination may increase the risk of torsades de pointes. The legacy description of a QT decrease is not consistent with the known effects of either drug.
How serious is the interaction between Anagrelide and Ivosidenib?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination if possible. If used together, monitor ECG and electrolytes regularly and reduce or stop therapy if QTc becomes markedly prolonged.
What other medicines interact with Anagrelide?
MediHelp also lists interactions of Anagrelide with, for example, Panobinostat, Pimozide, Thioridazine. The full list is on the Anagrelide page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
