दवाओं की अंतःक्रिया
Antithrombin alfa + Dabigatran etexilate
गंभीरता: गंभीर
Antithrombin alfa and Dabigatran etexilate: major interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Antithrombin potentiates inhibition of thrombin and factor Xa by heparins, and together with the direct thrombin inhibitor dabigatran may increase anticoagulant effect. This raises the risk of serious bleeding.
इस इंटरैक्शन का सरल भाषा में अर्थ
Antithrombin alfa and Dabigatran etexilate can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
ऐसा क्यों होता है
Additive anticoagulant effect through enhanced endogenous thrombin inhibition combined with direct thrombin inhibition.
क्या करें
Avoid concurrent use where possible and monitor for bleeding with coagulation tests (aPTT, ecarin or thrombin time) if both are essential. Use short-acting parenteral options when antithrombin replacement is needed.
फार्मासिस्ट से क्या पूछें
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Antithrombin alfa और Dabigatran etexilate की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Dabigatran etexilate के अन्य इंटरैक्शन
अक्सर पूछे जाने वाले प्रश्न
Can I take Antithrombin alfa with Dabigatran etexilate?
MediHelp rates the interaction as major. Antithrombin alfa and Dabigatran etexilate can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Antithrombin potentiates inhibition of thrombin and factor Xa by heparins, and together with the direct thrombin inhibitor dabigatran may increase anticoagulant effect. This raises the risk of serious bleeding.
How serious is the interaction between Antithrombin alfa and Dabigatran etexilate?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent use where possible and monitor for bleeding with coagulation tests (aPTT, ecarin or thrombin time) if both are essential. Use short-acting parenteral options when antithrombin replacement is needed.
What other medicines interact with Dabigatran etexilate?
MediHelp also lists interactions of Dabigatran etexilate with, for example, Defibrotide, Ketorolac, Mifepristone. The full list is on the Dabigatran etexilate page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
