दवाओं की अंतःक्रिया
Apraclonidine + Selegiline
गंभीरता: गंभीर
Apraclonidine and Selegiline: major interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Apraclonidine is an alpha-2 agonist, and labeling advises against its use with MAO inhibitors because of a possible rise in blood pressure. The pharmacological basis is not fully clear, and exposure is low with ophthalmic use, but the labeling warning remains.
इस इंटरैक्शन का सरल भाषा में अर्थ
Apraclonidine and Selegiline can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Apraclonidine belongs to Cardiovascular; Selegiline belongs to Central Nervous System.
ऐसा क्यों होता है
Mechanism is not established; possible altered catecholamine handling with MAO inhibition affecting blood pressure.
क्या करें
Avoid the combination where possible and choose another ocular hypotensive agent. If apraclonidine is essential, monitor blood pressure closely.
फार्मासिस्ट से क्या पूछें
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Apraclonidine और Selegiline की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Selegiline के अन्य इंटरैक्शन
- Amitriptyline + Selegiline निषिद्ध
- Amoxapine + Selegiline निषिद्ध
- Atomoxetine + Selegiline निषिद्ध
- Benzphetamine + Selegiline निषिद्ध
- Brimonidine + Selegiline निषिद्ध
- Buprenorphine long-acting + Selegiline निषिद्ध
Apraclonidine के अन्य इंटरैक्शन
अक्सर पूछे जाने वाले प्रश्न
Can I take Apraclonidine with Selegiline?
MediHelp rates the interaction as major. Apraclonidine and Selegiline can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Apraclonidine is an alpha-2 agonist, and labeling advises against its use with MAO inhibitors because of a possible rise in blood pressure. The pharmacological basis is not fully clear, and exposure is low with ophthalmic use, but the labeling warning remains.
How serious is the interaction between Apraclonidine and Selegiline?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination where possible and choose another ocular hypotensive agent. If apraclonidine is essential, monitor blood pressure closely.
What other medicines interact with Selegiline?
MediHelp also lists interactions of Selegiline with, for example, Amitriptyline, Amoxapine, Atomoxetine. The full list is on the Selegiline page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
