दवाओं की अंतःक्रिया
Baclofen + Buprenorphine long-acting
गंभीरता: गंभीर
Baclofen and Buprenorphine long-acting: major interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Baclofen with long-acting injectable buprenorphine can cause additive sedation and respiratory depression. The depot gives prolonged exposure, so the interaction cannot be quickly reversed by stopping the opioid.
इस इंटरैक्शन का सरल भाषा में अर्थ
Baclofen and Buprenorphine long-acting can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
ऐसा क्यों होता है
Additive CNS and respiratory depression from opioid receptor partial agonism and GABA-B agonism.
क्या करें
Use only when other treatments are inadequate, titrating baclofen to the lowest effective dose. Monitor for sedation and respiratory depression, particularly after baclofen initiation or increases.
फार्मासिस्ट से क्या पूछें
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Baclofen और Buprenorphine long-acting की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Baclofen के अन्य इंटरैक्शन
अक्सर पूछे जाने वाले प्रश्न
Can I take Baclofen with Buprenorphine long-acting?
MediHelp rates the interaction as major. Baclofen and Buprenorphine long-acting can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Baclofen with long-acting injectable buprenorphine can cause additive sedation and respiratory depression. The depot gives prolonged exposure, so the interaction cannot be quickly reversed by stopping the opioid.
How serious is the interaction between Baclofen and Buprenorphine long-acting?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use only when other treatments are inadequate, titrating baclofen to the lowest effective dose. Monitor for sedation and respiratory depression, particularly after baclofen initiation or increases.
What other medicines interact with Baclofen?
MediHelp also lists interactions of Baclofen with, for example, Alfentanil, Amobarbital, Belladonna and opium. The full list is on the Baclofen page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
