दवाओं की अंतःक्रिया
Bevacizumab + Sunitinib
गंभीरता: गंभीर
Bevacizumab and Sunitinib: major interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Combining these two anti-angiogenic agents has led to microangiopathic hemolytic anemia in patients with metastatic renal cell carcinoma. Hypertension and thrombocytopenia have also been seen, which makes the combination poorly tolerated.
इस इंटरैक्शन का सरल भाषा में अर्थ
Bevacizumab and Sunitinib can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Bevacizumab belongs to Oncology; Sunitinib belongs to Oncology.
ऐसा क्यों होता है
Combined inhibition of VEGF signalling at the ligand and receptor tyrosine kinase level causing endothelial injury and microangiopathy; exact mechanism is not fully defined.
क्या करें
Avoid concurrent use. If microangiopathic hemolytic anemia is suspected, check hemoglobin, platelets, LDH, haptoglobin and a blood smear, and stop the drugs.
फार्मासिस्ट से क्या पूछें
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Bevacizumab और Sunitinib की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Bevacizumab के अन्य इंटरैक्शन
Sunitinib के अन्य इंटरैक्शन
- Adagrasib + Sunitinib गंभीर
- Amiodarone + Sunitinib गंभीर
- Amisulpride + Sunitinib गंभीर
- Anagrelide + Sunitinib गंभीर
- Apalutamide + Sunitinib गंभीर
- Arsenic trioxide + Sunitinib गंभीर
अक्सर पूछे जाने वाले प्रश्न
Can I take Bevacizumab with Sunitinib?
MediHelp rates the interaction as major. Bevacizumab and Sunitinib can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Combining these two anti-angiogenic agents has led to microangiopathic hemolytic anemia in patients with metastatic renal cell carcinoma. Hypertension and thrombocytopenia have also been seen, which makes the combination poorly tolerated.
How serious is the interaction between Bevacizumab and Sunitinib?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent use. If microangiopathic hemolytic anemia is suspected, check hemoglobin, platelets, LDH, haptoglobin and a blood smear, and stop the drugs.
What other medicines interact with Bevacizumab?
MediHelp also lists interactions of Bevacizumab with, for example, Daunorubicin, Dengue vaccine, Doxorubicin. The full list is on the Bevacizumab page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
