दवाओं की अंतःक्रिया
Bismuth subsalicylate + Dichlorphenamide
गंभीरता: गंभीर
Bismuth subsalicylate and Dichlorphenamide: major interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Bismuth subsalicylate is hydrolysed to salicylate, and dichlorphenamide is a carbonic anhydrase inhibitor; with salicylates it can accumulate salicylate and worsen metabolic acidosis. Tachypnoea, lethargy and coma have been reported with high-dose aspirin.
इस इंटरैक्शन का सरल भाषा में अर्थ
Bismuth subsalicylate and Dichlorphenamide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Bismuth subsalicylate belongs to Gastrointestinal Tract; Dichlorphenamide belongs to Miscellaneous.
ऐसा क्यों होता है
Carbonic anhydrase inhibition causes metabolic acidosis and reduced salicylate renal clearance, raising salicylate levels
क्या करें
Avoid bismuth subsalicylate during dichlorphenamide therapy; if salicylate is needed use lowest dose and monitor acid-base status and symptoms of salicylism.
फार्मासिस्ट से क्या पूछें
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Bismuth subsalicylate और Dichlorphenamide की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Bismuth subsalicylate के अन्य इंटरैक्शन
Dichlorphenamide के अन्य इंटरैक्शन
अक्सर पूछे जाने वाले प्रश्न
Can I take Bismuth subsalicylate with Dichlorphenamide?
MediHelp rates the interaction as major. Bismuth subsalicylate and Dichlorphenamide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Bismuth subsalicylate is hydrolysed to salicylate, and dichlorphenamide is a carbonic anhydrase inhibitor; with salicylates it can accumulate salicylate and worsen metabolic acidosis. Tachypnoea, lethargy and coma have been reported with high-dose aspirin.
How serious is the interaction between Bismuth subsalicylate and Dichlorphenamide?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid bismuth subsalicylate during dichlorphenamide therapy; if salicylate is needed use lowest dose and monitor acid-base status and symptoms of salicylism.
What other medicines interact with Bismuth subsalicylate?
MediHelp also lists interactions of Bismuth subsalicylate with, for example, Warfarin, Acetylsalicylic acid, Amlodipine-benazepril. The full list is on the Bismuth subsalicylate page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
