दवाओं की अंतःक्रिया
Brigatinib + Ethinyl estradiol-norgestimate
गंभीरता: गंभीर
Brigatinib and Ethinyl estradiol-norgestimate: major interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Brigatinib may induce CYP3A4 and reduce hormonal contraceptive concentrations, with a risk of contraceptive failure. Brigatinib can cause fetal harm, so a loss of contraceptive efficacy is clinically important.
इस इंटरैक्शन का सरल भाषा में अर्थ
Brigatinib and Ethinyl estradiol-norgestimate can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Brigatinib belongs to Oncology; Ethinyl estradiol-norgestimate belongs to Endocrine.
ऐसा क्यों होता है
CYP3A4 induction by brigatinib increases the clearance of ethinyl estradiol and norgestimate.
क्या करें
Use an effective non-hormonal contraceptive during treatment and for at least 4 months after the last dose.
फार्मासिस्ट से क्या पूछें
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Brigatinib और Ethinyl estradiol-norgestimate की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Ethinyl estradiol-norgestimate के अन्य इंटरैक्शन
- Ethinyl estradiol-norgestimate + Fezolinetant निषिद्ध
- Ethinyl estradiol-norgestimate + Ombitasvir / paritaprevir / ritonavir and dasabuvir निषिद्ध
- Ethinyl estradiol-norgestimate + Tranexamic acid निषिद्ध
- Aminocaproic acid + Ethinyl estradiol-norgestimate गंभीर
- Amobarbital + Ethinyl estradiol-norgestimate गंभीर
- Anastrozole + Ethinyl estradiol-norgestimate गंभीर
Brigatinib के अन्य इंटरैक्शन
अक्सर पूछे जाने वाले प्रश्न
Can I take Brigatinib with Ethinyl estradiol-norgestimate?
MediHelp rates the interaction as major. Brigatinib and Ethinyl estradiol-norgestimate can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Brigatinib may induce CYP3A4 and reduce hormonal contraceptive concentrations, with a risk of contraceptive failure. Brigatinib can cause fetal harm, so a loss of contraceptive efficacy is clinically important.
How serious is the interaction between Brigatinib and Ethinyl estradiol-norgestimate?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use an effective non-hormonal contraceptive during treatment and for at least 4 months after the last dose.
What other medicines interact with Ethinyl estradiol-norgestimate?
MediHelp also lists interactions of Ethinyl estradiol-norgestimate with, for example, Fezolinetant, Ombitasvir / paritaprevir / ritonavir and dasabuvir, Tranexamic acid. The full list is on the Ethinyl estradiol-norgestimate page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
