दवाओं की अंतःक्रिया
Buprenorphine + Chlordiazepoxide-clidinium
गंभीरता: गंभीर
Buprenorphine and Chlordiazepoxide-clidinium: major interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Benzodiazepines combined with opioids such as buprenorphine can cause profound sedation, respiratory depression, coma and death. Regulators have issued boxed warnings for this class combination.
इस इंटरैक्शन का सरल भाषा में अर्थ
Buprenorphine and Chlordiazepoxide-clidinium can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Buprenorphine belongs to Musculoskeletal; Chlordiazepoxide-clidinium belongs to Gastrointestinal Tract.
ऐसा क्यों होता है
Additive CNS and respiratory depression via opioid and GABA-A receptor effects.
क्या करें
Avoid the combination when possible; if necessary, use the lowest doses for the shortest duration. Monitor respiratory rate and sedation and counsel patients and caregivers about warning signs.
फार्मासिस्ट से क्या पूछें
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Buprenorphine और Chlordiazepoxide-clidinium की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Chlordiazepoxide-clidinium के अन्य इंटरैक्शन
- Alfentanil + Chlordiazepoxide-clidinium गंभीर
- Alprazolam + Chlordiazepoxide-clidinium गंभीर
- Amobarbital + Chlordiazepoxide-clidinium गंभीर
- Belladonna and opium + Chlordiazepoxide-clidinium गंभीर
- Benzhydrocodone / acetaminophen + Chlordiazepoxide-clidinium गंभीर
- Brexanolone + Chlordiazepoxide-clidinium गंभीर
Buprenorphine के अन्य इंटरैक्शन
अक्सर पूछे जाने वाले प्रश्न
Can I take Buprenorphine with Chlordiazepoxide-clidinium?
MediHelp rates the interaction as major. Buprenorphine and Chlordiazepoxide-clidinium can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Benzodiazepines combined with opioids such as buprenorphine can cause profound sedation, respiratory depression, coma and death. Regulators have issued boxed warnings for this class combination.
How serious is the interaction between Buprenorphine and Chlordiazepoxide-clidinium?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination when possible; if necessary, use the lowest doses for the shortest duration. Monitor respiratory rate and sedation and counsel patients and caregivers about warning signs.
What other medicines interact with Chlordiazepoxide-clidinium?
MediHelp also lists interactions of Chlordiazepoxide-clidinium with, for example, Alfentanil, Alprazolam, Amobarbital. The full list is on the Chlordiazepoxide-clidinium page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
